Motif ID: HOX{A5,B5}.p2

Z-value: 1.252


Transcription factors associated with HOX{A5,B5}.p2:

Gene SymbolEntrez IDGene Name
HOXA5 3202 homeobox A5
HOXB5 3215 homeobox B5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HOXA5chr7_-_271497500.078.1e-01Click!
HOXB5chr17_-_44026042-0.049.0e-01Click!


Activity profile for motif HOX{A5,B5}.p2.

activity profile for motif HOX{A5,B5}.p2


Sorted Z-values histogram for motif HOX{A5,B5}.p2

Sorted Z-values for motif HOX{A5,B5}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOX{A5,B5}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_14457340 1.409 NM_001118885
NM_001118886
NM_001171942
NM_002063
GLRA2



glycine receptor, alpha 2



chr6_-_97391779 1.313 NM_001143957
NM_030784
GPR63

G protein-coupled receptor 63

chr19_-_13925192 1.266 NM_001146254
NM_001146255
PODNL1

podocan-like 1

chr19_-_54958326 1.168 NM_021733
TSKS
testis-specific serine kinase substrate
chr7_+_5289079 1.135 NM_001040661
NM_153247
SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chrX_+_51562894 0.953 NM_001005332
MAGED1
melanoma antigen family D, 1
chrX_+_48265107 0.889 NM_006579
EBP
emopamil binding protein (sterol isomerase)
chr7_-_106088565 0.885 NM_175884
FLJ36031
hypothetical protein FLJ36031
chr17_-_35911340 0.870 NM_032865
TNS4
tensin 4
chr1_+_144124547 0.870 NM_145277
NM_202004
NM_213652
NM_213653
HFE2



hemochromatosis type 2 (juvenile)



chr13_+_113574925 0.819 NM_001143945
GAS6
growth arrest-specific 6
chr4_-_115120251 0.786 NM_024590
ARSJ
arylsulfatase family, member J
chr1_+_28435167 0.779 NM_016311
NM_178190
NM_178191
ATPIF1


ATPase inhibitory factor 1


chr11_-_18566758 0.758 NM_001040697
NM_018314
UEVLD

UEV and lactate/malate dehyrogenase domains

chr4_-_73653331 0.757 NM_014243
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr10_+_35524835 0.757 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
CREM




cAMP responsive element modulator




chr11_-_56846246 0.744 TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr19_+_39437292 0.742 NM_014686
KIAA0355
KIAA0355
chrX_-_148394570 0.730 NM_000202
NM_001166550
NM_006123
IDS


iduronate 2-sulfatase


chr3_-_166397142 0.725 NM_014926
SLITRK3
SLIT and NTRK-like family, member 3
chr12_-_90096275 0.697 NM_133504
NM_133505
NM_133506
NM_133507
DCN



decorin



chr12_+_53241365 0.678 NM_001165975
PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr1_+_148020869 0.660 NM_000566
FCGR1A
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr17_-_72151314 0.655 NM_018414
ST6GALNAC1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
chr6_-_29503468 0.647 NM_013937
OR11A1
olfactory receptor, family 11, subfamily A, member 1
chrX_+_100220491 0.646 NM_021637
TMEM35
transmembrane protein 35
chr1_+_151270301 0.630 NM_003125
SPRR1B
small proline-rich protein 1B
chr12_-_51001407 0.629 NM_002282
KRT83
keratin 83
chr6_+_31651319 0.627 NM_000594
TNF
tumor necrosis factor
chr1_+_159462456 0.627 NM_032174
TOMM40L
translocase of outer mitochondrial membrane 40 homolog (yeast)-like
chr3_-_197023096 0.620 MUC4
mucin 4, cell surface associated
chr11_-_117600918 0.601 NM_001098526
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr8_+_110621092 0.588 NM_198120
EBAG9
estrogen receptor binding site associated, antigen, 9
chr19_-_51236113 0.578 NM_001002923
IGFL4
IGF-like family member 4
chr19_+_8023887 0.563 NM_005624
CCL25
chemokine (C-C motif) ligand 25
chr8_-_22841173 0.558 NM_144962
PEBP4
phosphatidylethanolamine-binding protein 4
chr17_+_18700385 0.552 PRPSAP2
phosphoribosyl pyrophosphate synthetase-associated protein 2
chr1_-_181540631 0.549 NM_170706
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr1_-_153444304 0.545 NM_007112
THBS3
thrombospondin 3
chr1_+_201711505 0.544 NM_002725
NM_201348
PRELP

proline/arginine-rich end leucine-rich repeat protein

chr15_-_49184764 0.535 NM_207381
TNFAIP8L3
tumor necrosis factor, alpha-induced protein 8-like 3
chr7_-_32077504 0.531 NM_001191059
NM_005020
PDE1C

phosphodiesterase 1C, calmodulin-dependent 70kDa

chr16_-_48960186 0.528 NM_001173984
NM_013263
BRD7

bromodomain containing 7

chr3_+_116824840 0.527 NM_001130064
NM_002045
GAP43

growth associated protein 43

chr16_-_1761504 0.521 NME3
non-metastatic cells 3, protein expressed in
chr18_-_44723116 0.509 NM_001190823
SMAD7
SMAD family member 7
chr1_+_55044323 0.506 NM_001110533
NM_152607
C1orf177

chromosome 1 open reading frame 177

chr19_-_56919032 0.506 NM_001523
HAS1
hyaluronan synthase 1
chr17_-_7036490 0.503


chr1_+_201711578 0.500 PRELP
proline/arginine-rich end leucine-rich repeat protein
chr15_-_46890475 0.498 NM_001194998
NM_014985
CEP152

centrosomal protein 152kDa

chr11_-_118477994 0.497 NM_001382
DPAGT1
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr1_+_116717552 0.495 ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr11_+_4621731 0.490 NM_152430
OR51E1
olfactory receptor, family 51, subfamily E, member 1
chr19_-_47040347 0.488 NM_173506
LYPD4
LY6/PLAUR domain containing 4
chr3_-_188339882 0.487 NM_052969
RPL39L
ribosomal protein L39-like
chr11_+_118259684 0.487 NM_001716
CXCR5
chemokine (C-X-C motif) receptor 5
chr6_+_31190505 0.477 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr4_+_123520044 0.468 NM_001159285
NM_001159295
ADAD1

adenosine deaminase domain containing 1 (testis-specific)

chr9_-_94680038 0.460 NM_001007101
NM_031486
ZNF484

zinc finger protein 484

chr9_-_28709302 0.458 NM_152570
LINGO2
leucine rich repeat and Ig domain containing 2
chr4_+_79002828 0.452 NM_020236
MRPL1
mitochondrial ribosomal protein L1
chr1_+_143326315 0.450 NM_001037675
NBPF10
NBPF9
NBPF8
neuroblastoma breakpoint family, member 10
neuroblastoma breakpoint family, member 9
neuroblastoma breakpoint family, member 8
chr12_+_7038240 0.444 NM_001734
NM_201442
C1S

complement component 1, s subcomponent

chr1_+_116717461 0.440 ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr1_+_111215343 0.438 NM_001040033
CD53
CD53 molecule
chr3_-_135131207 0.437 NM_025041
C3orf36
chromosome 3 open reading frame 36
chr6_-_41114905 0.434 NM_173561
UNC5CL
unc-5 homolog C (C. elegans)-like
chr1_+_160618143 0.430 NM_001085375
C1orf226
chromosome 1 open reading frame 226
chr1_-_150805852 0.420 NM_178435
LCE3E
late cornified envelope 3E
chr5_+_148766632 0.410 LOC728264
hypothetical LOC728264
chr6_-_42270671 0.404 NM_002098
GUCA1B
guanylate cyclase activator 1B (retina)
chr16_-_1761710 0.404 NM_002513
NME3
non-metastatic cells 3, protein expressed in
chr17_-_8004671 0.402 VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr1_+_200584421 0.399 NM_001167857
NM_001167858
NM_002481
PPP1R12B


protein phosphatase 1, regulatory (inhibitor) subunit 12B


chr3_-_197549588 0.398 TM4SF19
transmembrane 4 L six family member 19
chr1_-_152225312 0.398 NM_002870
RAB13
RAB13, member RAS oncogene family
chr3_+_11153778 0.398 NM_001098213
HRH1
histamine receptor H1
chr16_+_70117523 0.396 NM_005769
NM_001166395
CHST4

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4

chr19_-_63550712 0.392 A1BG
alpha-1-B glycoprotein
chr6_-_29081015 0.392 NM_001010877
ZNF311
zinc finger protein 311
chr1_+_113064711 0.390 NM_001004440
NM_182759
FAM19A3

family with sequence similarity 19 (chemokine (C-C motif)-like), member A3

chr7_+_142723340 0.390 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chrX_+_48253007 0.389 NM_203474
NM_203475
PORCN

porcupine homolog (Drosophila)

chr4_+_109033868 0.388 NM_001136257
NM_152621
SGMS2

sphingomyelin synthase 2

chr9_-_112010233 0.388 NM_001012993
C9orf152
chromosome 9 open reading frame 152
chr11_-_125055884 0.384 NM_001612
NM_020069
NM_020107
NM_020108
NM_020109
NM_020110
NM_020111
NM_020113
NM_020115
ACRV1








acrosomal vesicle protein 1








chr14_+_20306425 0.383 NM_022360
EDDM3B
epididymal protein 3B
chrX_+_148433970 0.382 NM_001171909
CXorf40A
chromosome X open reading frame 40A
chr4_-_45820686 0.380 NM_173536
GABRG1
gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr6_-_10527772 0.377 NM_001042425
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr17_-_20886680 0.377 NM_015276
USP22
ubiquitin specific peptidase 22
chr1_+_157676135 0.373 NM_012351
OR10J1
olfactory receptor, family 10, subfamily J, member 1
chr1_-_120240635 0.370 NM_021794
ADAM30
ADAM metallopeptidase domain 30
chr3_+_44746101 0.367 NM_145044
ZNF501
zinc finger protein 501
chr1_+_34993234 0.366 NM_005268
GJB5
gap junction protein, beta 5, 31.1kDa
chr8_-_66863841 0.366 NM_002603
PDE7A
phosphodiesterase 7A
chr3_+_11009419 0.366 NM_003042
SLC6A1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr1_-_109853808 0.361 NM_020703
AMIGO1
adhesion molecule with Ig-like domain 1
chr17_+_44325127 0.354 NM_001002027
NM_005175
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr5_+_128468785 0.353 ISOC1
isochorismatase domain containing 1
chrX_-_137777382 0.351 NM_001139502
FGF13
fibroblast growth factor 13
chr15_-_41728329 0.348 NM_054020
NM_172095
NM_172097
CATSPER2


cation channel, sperm associated 2


chr3_+_11009436 0.347 SLC6A1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr1_-_143706300 0.347 NM_001002812
NM_014644
NM_001002810
NM_001198834
NM_001195261
PDE4DIP




phosphodiesterase 4D interacting protein




chr1_+_147006065 0.346 NM_001102663
NBPF15
NBPF8
NBPF16
neuroblastoma breakpoint family, member 15
neuroblastoma breakpoint family, member 8
neuroblastoma breakpoint family, member 16
chr8_-_30826074 0.345 NM_031271
TEX15
testis expressed 15
chr1_-_148051859 0.345 NM_001123375
HIST2H3D
histone cluster 2, H3d
chr1_+_153846602 0.340 NM_018116
MSTO1
misato homolog 1 (Drosophila)
chr2_+_30223372 0.338 YPEL5
yippee-like 5 (Drosophila)
chr11_+_5574440 0.338 NM_001003818
NM_001198644
NM_001198645
NM_001003819
TRIM6


TRIM6-TRIM34
tripartite motif containing 6


TRIM6-TRIM34 readthrough
chr1_+_24518398 0.337 NM_198173
NM_198174
GRHL3

grainyhead-like 3 (Drosophila)

chr14_-_67353046 0.335 NM_015346
ZFYVE26
zinc finger, FYVE domain containing 26
chrX_-_107112244 0.333 NM_031273
TEX13B
testis expressed 13B
chr6_-_29563657 0.328 NM_052967
MAS1L
MAS1 oncogene-like
chr19_+_40824486 0.327 NM_014209
ETV2
ets variant 2
chr20_+_19863716 0.327 RIN2
Ras and Rab interactor 2
chr10_+_115300579 0.327 NM_001177660
HABP2
hyaluronan binding protein 2
chr4_+_110968594 0.325 NM_006583
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr14_+_52243645 0.322 NM_002806
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr19_+_45797413 0.321 LTBP4
latent transforming growth factor beta binding protein 4
chr1_+_146843980 0.320 NM_001102663
NBPF15
NBPF8
NBPF16
neuroblastoma breakpoint family, member 15
neuroblastoma breakpoint family, member 8
neuroblastoma breakpoint family, member 16
chr19_-_43492348 0.318 NM_033557
YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr11_+_108798084 0.318 C11orf87
chromosome 11 open reading frame 87
chr1_+_151967164 0.316 NM_023015
INTS3
integrator complex subunit 3
chr2_-_219881937 0.312 PTPRN
protein tyrosine phosphatase, receptor type, N
chr3_+_23961739 0.312 NM_005126
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr9_-_124370576 0.308 NM_001004454
OR1L8
olfactory receptor, family 1, subfamily L, member 8
chr1_-_143706265 0.305 PDE4DIP
phosphodiesterase 4D interacting protein
chr6_+_155626838 0.300 NM_001001346
CLDN20
claudin 20
chr16_+_2749934 0.298


chr22_+_21870293 0.298


chr3_-_197549640 0.297 NM_138461
TM4SF19
transmembrane 4 L six family member 19
chr1_+_116718011 0.293 NM_001160233
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr11_-_8911110 0.292 NM_020643
C11orf16
chromosome 11 open reading frame 16
chr10_+_35524060 0.291 NM_182717
NM_182718
NM_182719
NM_182720
CREM



cAMP responsive element modulator



chr14_-_23090606 0.291 NM_033400
ZFHX2
zinc finger homeobox 2
chr1_+_24701363 0.290 RCAN3
RCAN family member 3
chr14_-_19572756 0.290 NM_001004714
OR4K13
olfactory receptor, family 4, subfamily K, member 13
chr11_+_20027185 0.289 NAV2
neuron navigator 2
chrX_-_37964924 0.287 NM_001170750
NM_001170751
NM_001170752
NM_006307
SRPX



sushi-repeat containing protein, X-linked



chr1_-_143706196 0.287 PDE4DIP
phosphodiesterase 4D interacting protein
chr17_-_8241868 0.286 NM_001146684
RNF222
ring finger protein 222
chrX_+_15718494 0.283 NM_005089
ZRSR2
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
chr12_-_123914219 0.280 SCARB1
scavenger receptor class B, member 1
chr11_+_125208420 0.280 NM_001144874
PATE4
prostate and testis expressed 4
chr17_-_36276987 0.280 NM_000223
KRT12
keratin 12
chr11_-_111287657 0.279 NM_001885
CRYAB
crystallin, alpha B
chr19_-_1966628 0.278 NM_017797
BTBD2
BTB (POZ) domain containing 2
chr1_+_116717404 0.273 ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr3_+_190372456 0.269 NM_198485
TPRG1
tumor protein p63 regulated 1
chrX_-_130250715 0.269 NM_001170963
IGSF1
immunoglobulin superfamily, member 1
chr5_-_35974493 0.266 NM_001042625
NM_144647
CAPSL

calcyphosine-like

chr1_+_246578699 0.264 NM_001001918
OR14C36
olfactory receptor, family 14, subfamily C, member 36
chr7_-_139948780 0.264 NM_015689
DENND2A
DENN/MADD domain containing 2A
chr11_+_66152309 0.262


chr1_-_167947301 0.261 NM_000655
SELL
selectin L
chr12_+_52806103 0.261 LOC400043
hypothetical LOC400043
chr16_-_56562512 0.257 NM_001135639
NM_001297
CNGB1

cyclic nucleotide gated channel beta 1

chr1_-_37792414 0.256 NM_024700
SNIP1
Smad nuclear interacting protein 1
chrX_-_116991728 0.254 NM_033495
NM_001168300
KLHL13

kelch-like 13 (Drosophila)

chrX_-_23955223 0.254 NM_030624
KLHL15
kelch-like 15 (Drosophila)
chrX_-_153500584 0.251 NM_001327
NM_139250
CTAG1B
CTAG1A
cancer/testis antigen 1B
cancer/testis antigen 1A
chr9_-_131626261 0.251 NM_000113
TOR1A
torsin family 1, member A (torsin A)
chr19_-_57290777 0.250 NM_001136499
ZNF841
zinc finger protein 841
chr7_+_116238309 0.248 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr6_-_41230003 0.248 NM_178174
TREML1
triggering receptor expressed on myeloid cells-like 1
chr1_+_245720992 0.247 NM_001004698
OR2W5
olfactory receptor, family 2, subfamily W, member 5
chr1_-_159459814 0.244 APOA2
apolipoprotein A-II
chr22_+_29333069 0.243 NM_000355
NM_001184726
TCN2

transcobalamin II

chr11_-_118477739 0.243 DPAGT1
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr5_+_357290 0.242 NM_020731
AHRR
aryl-hydrocarbon receptor repressor
chr12_-_11313907 0.242 NM_006249
PRB3
proline-rich protein BstNI subfamily 3
chr19_-_52614151 0.242 MEIS3
Meis homeobox 3
chr1_-_71319559 0.242 NM_005455
NM_203350
ZRANB2

zinc finger, RAN-binding domain containing 2

chr2_+_151922350 0.241 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr7_+_90063543 0.241 CDK14
cyclin-dependent kinase 14
chr3_+_45405059 0.239 NM_015340
LARS2
leucyl-tRNA synthetase 2, mitochondrial
chr3_+_73128629 0.238 PPP4R2
protein phosphatase 4, regulatory subunit 2
chr5_+_17270474 0.238 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr6_+_3063860 0.236 NM_004332
BPHL
biphenyl hydrolase-like (serine hydrolase)
chr14_+_23852152 0.234 NM_181657
LTB4R
leukotriene B4 receptor
chr20_-_43693320 0.234 NM_147198
WFDC9
WAP four-disulfide core domain 9
chr9_+_33785558 0.234 NM_002771
PRSS3
protease, serine, 3
chr3_+_73128667 0.232 PPP4R2
protein phosphatase 4, regulatory subunit 2
chr1_-_120189301 0.230 NM_001047980
NBPF7
neuroblastoma breakpoint family, member 7
chr11_+_36274300 0.228 NM_001160167
PRR5L
proline rich 5 like
chr20_+_32598352 0.227 NM_181509
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr12_+_43972732 0.226 NM_001142678
ANO6
anoctamin 6
chr12_+_16391795 0.224 NM_020300
NM_145791
MGST1

microsomal glutathione S-transferase 1

chr2_+_108590032 0.224 NM_001193482
LIMS1
LIM and senescent cell antigen-like domains 1
chrX_+_54850832 0.221 NM_177433
MAGED2
melanoma antigen family D, 2
chr2_-_74498351 0.220 NM_001145054
C2orf81
chromosome 2 open reading frame 81
chr3_-_46481346 0.220 NM_002343
LTF
lactotransferrin
chrX_+_154650590 0.218 NM_005840
SPRY3
sprouty homolog 3 (Drosophila)
chr12_+_63090008 0.218 XPOT
exportin, tRNA (nuclear export receptor for tRNAs)
chr19_-_7598204 0.217 XAB2
XPA binding protein 2
chrX_+_37777730 0.215 NM_001163334
SYTL5
synaptotagmin-like 5
chr2_-_37047113 0.215 NM_003162
STRN
striatin, calmodulin binding protein
chr16_+_31446703 0.213 NM_016633
AHSP
alpha hemoglobin stabilizing protein

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.